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<front>
<journal-meta>
<journal-id journal-id-type="issn">1556-5009</journal-id>
<journal-title-group>
<journal-title>Journal of Muslim Mental Health</journal-title>
</journal-title-group>
<issn pub-type="epub">1556-5009</issn>
<publisher>
<publisher-name>Michigan Publishing</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="doi">10.3998/jmmh.5390</article-id>
<article-categories>
<subj-group>
<subject>Original article</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>Suicidal Ideation Among Pakistani Youth During the COVID-19 Outbreak: Moderating Role of Religious Orientation and Social Connectedness</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author" corresp="yes">
<name>
<surname>Muneeb</surname>
<given-names>Noor Ul Ain</given-names>
</name>
<email>annietabrez3@gmail.com</email>
<xref ref-type="aff" rid="aff-1">*</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Hassan</surname>
<given-names>Sumara Masood Ul</given-names>
</name>
<email>dr.sumara@s3h.nust.edu.pk</email>
<xref ref-type="aff" rid="aff-2">&#8224;</xref>
</contrib>
</contrib-group>
<aff id="aff-1"><label>*</label>Department of Behavioral Sciences, S3H, National University of Sciences and Technology, H-12, Islamabad, Pakistan</aff>
<aff id="aff-2"><label>&#8224;</label>Department of Behavioral Sciences, S3H, National University of Sciences and Technology, H-12, Islamabad, Pakistan</aff>
<pub-date publication-format="electronic" date-type="pub" iso-8601-date="2025-10-01">
<day>01</day>
<month>10</month>
<year>2025</year>
</pub-date>
<pub-date pub-type="collection">
<year>2025</year>
</pub-date>
<volume>18</volume>
<issue>3</issue>
<fpage>1</fpage>
<lpage>16</lpage>
<permissions>
<copyright-statement>Copyright: &#x00A9; 2025 The Author(s)</copyright-statement>
<copyright-year>2025</copyright-year>
<license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by/4.0/">
<license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International License (CC-BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. See <uri xlink:href="http://creativecommons.org/licenses/by/4.0/">http://creativecommons.org/licenses/by/4.0/</uri>.</license-p>
</license>
</permissions>
<self-uri xlink:href="https://journals.publishing.umich.edu/jmmh/article/10.3998/jmmh.5390/"/>
<abstract>
<p>The COVID-19 pandemic and sudden economic decline led to a drastic surge in suicidal ideation rates among the young population, warranting prevention before its progression to behavior. The current body of research has not yet adequately captured the underlying mechanism between psychological strain and suicidal ideation and the protective role of social determinants in preventing suicidal ideation. This study aimed to explore the mitigating roles of religious orientation and social connectedness between psychological strain and suicidal ideation among Muslim youth during the COVID-19 outbreak between May 2020 and August 2020. This study also explored the moderating role of social connectedness in the mediation of depression between psychological strain and suicidal ideation. University students selected using convenience sampling (N = 400) completed an online questionnaire. Intrinsic religious orientation (&#946; = &#8211;.006, p &lt; 0.05) and social connectedness (&#946; = &#8211;.002, p &lt; 0.05) significantly mitigated the impact of psychological strain on suicidal ideation. he paths between psychological strain and depression (&#946; = &#8211;.002, p &lt; 0.001), and between depression and suicidal ideation were significantly moderated by social connectedness (&#946; = &#8211;.0053, p &lt; 0.05). Protective factors, such as intrinsic religious orientation (i.e., having an inward expression of religious beliefs, in which people use religion as the framework for their lives) and a perceived sense of connectedness must be taken into account when devising intervention programs against depression and suicidal ideation. This study underscores the importance of prevention programs against suicide to protect the youth living with strains and debilitating thoughts of ending their lives.</p>
</abstract>
<kwd-group>
<kwd>Young adults</kwd>
<kwd>psychological strain</kwd>
<kwd>suicidal ideation</kwd>
<kwd>social connectedness</kwd>
<kwd>Pakistan</kwd>
</kwd-group>
</article-meta>
</front>
<body>
<sec>
<title>1. Introduction</title>
<p>Suicide is the third leading cause of death among youth aged 15&#8211;29 years. Seventy-three percent of global suicides occur in low- and middle-income countries (LMICs), with Pakistan being among them. For every suicidal death, there are many more contemplating suicide or attempting to end their lives (<xref ref-type="bibr" rid="B95">World Health Organization [WHO], 2025</xref>). Most Muslim-majority countries, like Pakistan, fall into LMICs (<xref ref-type="bibr" rid="B9">Arafat et al., 2022</xref>). Due to legal and religious prohibitions on suicide within Muslim-majority countries, data on suicide is seldom collected and statistically reported to the World Health Organization (WHO) (<xref ref-type="bibr" rid="B8">Arafat et al., 2021</xref>; <xref ref-type="bibr" rid="B26">Eskin et al., 2021</xref>; <xref ref-type="bibr" rid="B56">Lew et al., 2022</xref>). Even when reported, the numbers in are likely significantly lower than the rates quoted by some studies conducted in such areas. Probable suicidal deaths can be attributed to other external causes of death, and therefore suicide can go unidentified (<xref ref-type="bibr" rid="B56">Lew et al., 2022</xref>; <xref ref-type="bibr" rid="B72">Pritchard et al., 2020</xref>; <xref ref-type="bibr" rid="B71">Pritchard &amp; Amanullah, 2007</xref>). Likewise, in Pakistan, official statistics on suicide are not reported or published in morbidity surveys due to administrative and legal concerns. Consequently, due to religious and social stigma, suicidal cases can be either reported as accidents or as other causes of death (<xref ref-type="bibr" rid="B11">Asad et al., 2022</xref>).</p>
<p>Suicide is an act of taking one&#8217;s own life, whereas suicidal ideation (SI) is defined as having thoughts, ideas, and the desire to end one&#8217;s own life (<xref ref-type="bibr" rid="B36">Harmer et al., 2024</xref>). Suicidal ideation is on a spectrum of intensity, ranging from a general desire die, progressing to having a dedicated plan and intent to end one&#8217;s life. These thoughts are a substantial pathway to suicide attempts (<xref ref-type="bibr" rid="B38">Herba et al., 2007</xref>; <xref ref-type="bibr" rid="B48">Klonsky et al., 2016</xref>) and remain one of the strongest predictors of future suicide (<xref ref-type="bibr" rid="B36">Harmer et al., 2024</xref>). The idea of a prompt suicidal act without ideation seems improbable, as a recent study highlights that 90% of individuals who die by suicide suffer from a psychiatric illness (<xref ref-type="bibr" rid="B58">Mann et al., 2021</xref>). Understanding the intricacies of SI, its etiology, and protective factors is a crucial step in early intervention and reducing the likelihood of suicide (<xref ref-type="bibr" rid="B36">Harmer et al., 2024</xref>). The prevalence rate for SI (11.5%) is much higher than that of attempts (3.1%) (<xref ref-type="bibr" rid="B16">Borges et al., 2008</xref>), yet most of the literature is dedicated to suicidal behavior, inadequately addressing ideation, attempt, and behavior combined (<xref ref-type="bibr" rid="B20">Castellv&#237; et al., 2017</xref>; <xref ref-type="bibr" rid="B61">Miranda-Mendiz&#225;bal et al., 2017</xref>). Given the global rise in suicide rates, especially during the pandemic, a comprehensive understanding and effective management of SI is imperative for timely intervention against suicide (<xref ref-type="bibr" rid="B99">Yan et al., 2023</xref>).</p>
<p>Xiong and colleagues (<xref ref-type="bibr" rid="B98">2020</xref>) reported unprecedentedly high rates of mental disorders during COVID-19 globally, with young people at the highest risk. The suicide-related consequences of the pandemic are expected to be worse in countries facing economic decline with insufficient welfare support, like Pakistan (<xref ref-type="bibr" rid="B35">Gunnell et al., 2020</xref>). Uncertainty and panic elicited by COVID-19 exacerbate the risk of SI, with social isolation making the situation worse (<xref ref-type="bibr" rid="B79">Sher, 2020</xref>). A recent systematic review and meta-analysis conducted among Muslim-majority countries indicated that the prevalence of lifetime SI was highest in Southeast Asia, but the 12-month prevalence of SI among university students is highest (16.8%) in the Eastern Mediterranean region, which includes Pakistan (<xref ref-type="bibr" rid="B7">Arafat et al., 2023</xref>).</p>
<p>The suicidal crisis in Pakistan is no different than the crisis present globally, as an increase in suicide rates has been observed among Pakistani youth, who constitute 64% of the total population (<xref ref-type="bibr" rid="B42">Imran et al., 2022</xref>; <xref ref-type="bibr" rid="B66">Naveed et al., 2023</xref>; <xref ref-type="bibr" rid="B100">Yousafzai et al., 2022</xref>). Most of these cases were reported to be individuals under the age of 30 years, warranting the need for preventive strategies and programs for youth (<xref ref-type="bibr" rid="B66">Naveed et al., 2023</xref>).</p>
<p>The recent amendment to Section 325 of the Pakistan Penal Code, which decriminalized suicide attempts in Pakistan, represents a progressive step toward improving suicide reporting. However, suicide remains an under-researched topic in the country (<xref ref-type="bibr" rid="B43">Khan &amp; Ali Hyder, 2006</xref>). The existing literature has not sufficiently explored effective prevention strategies or protective factors that can mitigate suicide at the ideation stage, preventing its progression to behavior (<xref ref-type="bibr" rid="B63">Muneeb &amp; Hassan, 2023b</xref>; <xref ref-type="bibr" rid="B25">Eman et al., 2025</xref>). Against this backdrop, the present study seeks to address SI by examining its risk factors and protective mechanisms.</p>
<p>To prevent SI, it is crucial to understand the pathway that underlies it and to inhibit it before its progression (<xref ref-type="bibr" rid="B44">Khan et al., 2008</xref>). The Strain Theory of Suicide (STS) identifies psychological strain (PS) as a consistent and significant predictor of a suicidal mindset (<xref ref-type="bibr" rid="B101">Zhang, 2019</xref>). Psychological Strain is described as the &#8220;mental anguish of a person deciding on two correspondingly significant, however contradictory, social facts, which pull an individual in opposite directions&#8221; (<xref ref-type="bibr" rid="B106">Zhang et al., 2011</xref>). To escape from mental agony and attain psychological balance, to some, dying may appear more rewarding than continuing to live. In the form of inward release, it results in suicidal thoughts. Though the association between PS and SI has been established theoretically and empirically (<xref ref-type="bibr" rid="B104">Zhang et al., 2017</xref>; <xref ref-type="bibr" rid="B107">Zhao &amp; Zhang, 2018</xref>), the underlying pathway is yet to be explored (<xref ref-type="bibr" rid="B83">Sun et al., 2020</xref>). An understanding of these mechanisms and earlier intervention is crucial for its effective management against suicide.</p>
<p>The pathways of PS involve mental disorders mediating the path between PS and SI, whereas social and moral factors can protect against SI. The excess or inadequacy of social integration and moral regulation is deemed a predictor of suicide (<xref ref-type="bibr" rid="B101">Zhang, 2019</xref>). Depression among mental disorders is the strongest predictor of SI (<xref ref-type="bibr" rid="B74">Ran et al., 2015</xref>). Psychological Strain was found to be significantly associated with SI and depression (<xref ref-type="bibr" rid="B106">Zhang et al., 2011</xref>; <xref ref-type="bibr" rid="B105">Zhang &amp; Lv, 2014</xref>), but the increase in PS and depression may not necessarily predict an increase in SI (<xref ref-type="bibr" rid="B107">Zhao &amp; Zhang, 2018</xref>). Similarly, only a specific combination of strain and depression predicted SI beyond demographics in other studies (<xref ref-type="bibr" rid="B103">Zhang et al., 2016</xref>; <xref ref-type="bibr" rid="B107">Zhao &amp; Zhang, 2018</xref>). This illustrates that despite PS being a predictor of depression and SI, the path might be contingent upon other moral and social factors (<xref ref-type="bibr" rid="B101">Zhang, 2019</xref>), like religious orientation (RO) and social connectedness (SC). It is found that depression can mediate the relationship between PS and SI (<xref ref-type="bibr" rid="B62">Muneeb &amp; Hassan, 2023a</xref>; <xref ref-type="bibr" rid="B83">Sun et al., 2020</xref>), but it is not clear from empirical evidence whether the level of SC can confound this relationship. It is hypothesized that the mediation might be contingent upon other factors (<xref ref-type="bibr" rid="B101">Zhang, 2019</xref>) that buffer the impact of PS and depression on SI, such as SC and RO.</p>
</sec>
<sec>
<title>2. Role of Social Connectedness as a Moderator between Psychological Strain and Suicidal Ideation</title>
<sec>
<title>2.1 Social connectedness</title>
<p>Social connectedness (SC) is &#8220;how one views oneself with the external world.&#8221; (<xref ref-type="bibr" rid="B52">Lee &amp; Robbins, 1995</xref>). It includes all dimensions of social relations, including domestic, peer networks, and the community in general. Daily interactions are also included in one&#8217;s sense of SC (<xref ref-type="bibr" rid="B86">Townsend &amp; McWhirter, 2005</xref>). It can be defined as having a lasting and pervasive sense of relational intimacy with the social world (<xref ref-type="bibr" rid="B52">Lee &amp; Robbins, 1995</xref>). This sense of connectedness matures from adolescence to adulthood as one gradually builds trust in social relationships and gets comfortable in roles like a partner, parent, or colleague. Alternatively, a person who does not feel connected most likely struggles in social relationships (<xref ref-type="bibr" rid="B51">Lee et al., 2001</xref>).</p>
</sec>
<sec>
<title><italic>2.2 Psychological Strain and Social Connectedness</italic></title>
<p>The STS relates suicide to social integration, as excessive social integration may lead to deprivation strain. Frequent social interactions can stimulate comparison, where one may feel less than others or relatively deprived. Contrarily, the inadequacy of social integration can lead to coping strain, as facing ordeals may seem more taxing when facing them alone rather than with social or personal relations (<xref ref-type="bibr" rid="B101">Zhang, 2019</xref>).</p>
<p>To our knowledge, the role of SC as a moderator in the relationship between PS and SI has not been previously addressed. A moderated mediation model was tested in which psychological pain mediated the association of bullying and SI. Family togetherness and peer support moderated the mediation among middle and high school students (<xref ref-type="bibr" rid="B13">Bao et al., 2020</xref>). Another study provided evidence for social support mitigating the effects of PS on suicidal behavior among professionals in China (<xref ref-type="bibr" rid="B54">Lew et al., 2020</xref>). This study aims to address SC as an overarching construct of connectedness (<xref ref-type="bibr" rid="B92">Williams &amp; Galliher, 2006</xref>).</p>
</sec>
<sec>
<title><italic>2.3 Social Connectedness and Suicidal Ideation</italic></title>
<p>An individual&#8217;s level of SC guides their feelings, thinking, and behavior in various social settings. The perception of low-connected people of their environment might be cold and negative, as opposed to that of high-connected people, which might be positive and welcoming (<xref ref-type="bibr" rid="B51">Lee et al., 2001</xref>). Perceived low levels of connectedness may lead to frustration and loss of sense of belongingness, resulting in chronic loneliness, lower self-worth, and social mistrust (<xref ref-type="bibr" rid="B53">Lee &amp; Robbins, 1998</xref>). Problems with SC elucidate a more tenacious, global incapacity to connect with the social world (<xref ref-type="bibr" rid="B92">Williams &amp; Galliher, 2006</xref>). Chronic isolation can be traumatic, affecting areas of functioning and development (<xref ref-type="bibr" rid="B52">Lee &amp; Robbins, 1995</xref>). It directly leads to feelings of loneliness, which has been a strong predictor of SI in both men and women (<xref ref-type="bibr" rid="B60">McClelland et al., 2020</xref>; <xref ref-type="bibr" rid="B81">Stravynski &amp; Boyer, 2001</xref>).</p>
<p>As mentioned earlier, a large body of literature on suicide focuses on reactivity rather than prevention. The primary focus is on risk elements when, in fact, protective elements, if powerful enough, can mitigate the impact of risk factors (<xref ref-type="bibr" rid="B77">S&#225;nchez-Teruel &amp; Robles-Bello, 2014</xref>). As protective elements against SI, both SC and social support (SS) have significance in the literature. In terms of relative importance, SC (17.6% variance) has a far greater protective role than SS (0.5% variance) against SI (<xref ref-type="bibr" rid="B76">Reyes, 2020</xref>). Empirical evidence exists to support that teacher, peer, familial, and school connectedness are protective factors against suicide (<xref ref-type="bibr" rid="B90">Whitlock et al., 2014</xref>). Parental connectedness significantly predicted a decrease in suicide (<xref ref-type="bibr" rid="B34">Gunn et al., 2018</xref>). School connectedness and community connectedness negatively predicted SI in cross-sectional studies and meta-analyses (<xref ref-type="bibr" rid="B28">Foster et al., 2017</xref>; <xref ref-type="bibr" rid="B59">Marraccini &amp; Brier, 2017</xref>). Social connectedness was positively related to self-esteem, especially among females in Pakistan (<xref ref-type="bibr" rid="B27">Fatima et al., 2017</xref>). Respondents hailing from single-parent families had persistently higher rates of SI (68.3%) than those from two-parent families (33.3%) (<xref ref-type="bibr" rid="B32">Ghazanfar et al., 2015</xref>). These studies have indirectly alluded to SS and its constituents, but no study has addressed SC as a construct in Pakistan or its mitigating effects upon SI.</p>
</sec>
</sec>
<sec>
<title>3. Role of Religious Orientation as a Moderator between Strain and Suicidal Ideation</title>
<sec>
<title>3.1 Psychological Strain and Religious Orientation</title>
<p>Religious orientation is &#8220;the degree of one&#8217;s involvement and personal significance attached to a sacred system&#8221; (<xref ref-type="bibr" rid="B15">Bjarnason, 2007</xref>). Extrinsic religious orientation (ERO) is a way of acquiring some self-serving end, where religion is utilized as an instrument that endorses social support, comfort, and self-esteem. Intrinsic religious orientation (IRO) is described as religion being an ultimate end in itself. Intrinsically religious people are exhilarated by a promise for personal spiritual development and a deeper, more meaningful relationship with God. (<xref ref-type="bibr" rid="B15">Bjarnason, 2007</xref>; <xref ref-type="bibr" rid="B23">Darvyri et al., 2014</xref>). People with IRO internalize their beliefs and use them as a framework to view their life, its purpose, and their contributions to it (<xref ref-type="bibr" rid="B46">King et al., 2020</xref>; <xref ref-type="bibr" rid="B57">Liang &amp; Ketcham, 2017</xref>).</p>
<p>The STS regards excess or inadequacy of social integration and moral regulation as predictors of suicide. Excessive moral regulation can lead to value strain, whereas inadequate moral regulation can lead to aspiration strain (<xref ref-type="bibr" rid="B101">Zhang, 2019</xref>). Psychological strain is not studied with religious orientation, despite being an important determinant of depression and SI (<xref ref-type="bibr" rid="B103">Zhang et al., 2016</xref>, <xref ref-type="bibr" rid="B104">2017</xref>; <xref ref-type="bibr" rid="B107">Zhao &amp; Zhang, 2018</xref>). In a few studies, psychological distress and pressure were assessed with RO among Muslim students, elucidating a significant negative association (<xref ref-type="bibr" rid="B17">Butt, 2014</xref>; <xref ref-type="bibr" rid="B45">Kidwai et al., 2014</xref>) . However, these studies referred to unidirectional stress and not strain. For it to be considered a strain, two contradicting social facts need to be pulling an individual in the opposite directions, making it more detrimental, exacerbating, and frightening for an individual (<xref ref-type="bibr" rid="B101">Zhang, 2019</xref>).</p>
<p>Religious orientation was addressed with PS among studies conducted in rural China, but the inquiry remained limited to a single question of individuals being either religious or not religious (<xref ref-type="bibr" rid="B105">Zhang &amp; Lv, 2014</xref>; <xref ref-type="bibr" rid="B107">Zhao &amp; Zhang, 2018</xref>). Contrary to the Western sample, among Chinese students, those reported to believe in religion or were religious had higher levels of depression and SI as compared to those who were not. Among the Chinese sample, RO was a risk factor for SI (<xref ref-type="bibr" rid="B103">Zhang et al., 2016</xref>). Non-religious students were less likely to be depressed (<xref ref-type="bibr" rid="B54">Lew et al., 2020</xref>), though a single item limits the reliability of the findings. Overcoming this limitation in a psychological autopsy study, RO was studied using four items with dichotomous responses. The comparison was made between completed suicides and living controls, where religious orientation was found to be stronger for suicides as compared to controls (<xref ref-type="bibr" rid="B106">Zhang et al., 2011</xref>). As most of these studies were conducted in China, which is declared an atheist country, where prayer or going to church is considered to be deviant behavior (<xref ref-type="bibr" rid="B106">Zhang et al., 2011</xref>), religion may not be a protective factor against psychopathology, mental disorder, and suicidality (<xref ref-type="bibr" rid="B102">Zhang et al., 2024</xref>). Psychological strain in these cases may be experienced as a result of going against the norm (<xref ref-type="bibr" rid="B106">Zhang et al., 2011</xref>).</p>
</sec>
<sec>
<title><italic>3.2 Religious Orientation and Suicidal Ideation</italic></title>
<p>The protective role of religion against suicide has been a frequent debate in the literature across many religions (<xref ref-type="bibr" rid="B22">Cook, 2014</xref>). Although religion can play a protective role against suicide, the role might be conditional on culture-related implications and on association with a specific religion (<xref ref-type="bibr" rid="B50">Lawrence et al., 2016</xref>). Similarly, religious attendance significantly predicted decreased suicide attempts among those suffering from mental illnesses, even after controlling for social support (<xref ref-type="bibr" rid="B75">Rasic et al., 2009</xref>). A meta-analysis indicated that religion played a significant defensive role against suicide in both Western and old cultures, but not in Eastern countries (<xref ref-type="bibr" rid="B97">Wu et al., 2015</xref>). Likewise, in a cross-cultural study, religiosity was strong in Brazil and South Africa, but not in India and Vietnam (<xref ref-type="bibr" rid="B80">Sisask et al., 2010</xref>). This posits that the association between RO and suicide can vary based on cultural settings and affiliation with a particular religion. The available empirical evidence for suicidal behavior underscores the exclusive importance of SI, and the number of studies discretely focusing on ideation is rare. The levels of SI were found to be higher among depressed patients who regarded religion as more important and those who attended religious services (<xref ref-type="bibr" rid="B50">Lawrence et al., 2016</xref>).</p>
<p>In a country like Pakistan, where 96% of the population is Muslim (<xref ref-type="bibr" rid="B87">USCIRF, 2022</xref>), there is a need to explore whether RO acts as a risk or protective element regarding SI, by studying the moderating role of RO between PS and SI among young Muslim students.</p>
</sec>
<sec>
<title><italic>3.3 The Present Study</italic></title>
<p>This study extends previous research in several aspects. First, it focused exclusively on SI among young Muslim students aged 18 to 30. Second, the process-oriented approach was used to explore the moderating mechanisms between PS and SI. As shown in <xref ref-type="fig" rid="F1">Figure 1</xref>, this study explored the moderating role of SC and RO in the association between PS and SI. In addition, it explored the moderated mediation of SC between PS and SI among students.</p>
<fig id="F1">
<label>Figure 1</label>
<caption>
<p>Conceptual framework indicating the hypothesized relationships between the variables.</p>
</caption>
<graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="jmmh-5390_hassan-g1.png"/>
</fig>
</sec>
</sec>
<sec>
<title>4. Methods</title>
<sec>
<title>4.1 Participants and Procedure</title>
<p>To collect data from a large sample during the lockdown, the survey method was deemed appropriate. A convenience sampling technique was used to collect data from different universities in Rawalpindi and Islamabad, Pakistan. Four hundred undergraduate, graduate, and doctoral students aged 18 to 30 years participated in the study. The data collection process commenced after formal approval from the Institutional Review Board. The data was collected online using a convenience sampling technique, during the COVID-19 lockdown between May 2020 and August 2020. The sampling population was students of the age range of 18 to 30 years from universities in Rawalpindi and Islamabad. The sample size was calculated using a sample size calculator. Informed consent was obtained from all participants. They were debriefed on the rationale of the study, their prospective inputs, and their right to withdraw from the study at any point. The survey information was kept confidential, and the personal information of participants was concealed. The survey was conducted using a self-report questionnaire comprising five categories: a socio-demographic section followed by scales to assess SI, PS, SC, depression, and RO.</p>
</sec>
<sec>
<title><italic>4.2 Measures</italic></title>
<sec>
<title>4.2.1 Suicidal Ideation</title>
<p>The Suicide Ideation Scale (<xref ref-type="bibr" rid="B14">Beck et al., 1979</xref>) was administered to assess the intensity and severity of SI of participants over the past week. This is a 10-item self-report measure that has been tested and validated among Pakistani students (<xref ref-type="bibr" rid="B41">Ijaz &amp; Ahmed, 2018</xref>).</p>
</sec>
<sec>
<title>4.2.2 Psychological Strain</title>
<p>The Psychological Strain Scale (PSS-40) was administered to assess value, deprivation, aspiration, and coping strain. The scale consists of 40 items with a 5-point Likert scale. The scale is a valid and reliable measure to assess strain among students in Pakistan (<xref ref-type="bibr" rid="B62">Muneeb &amp; Hassan, 2023a</xref>).</p>
</sec>
<sec>
<title>4.2.3 Depression</title>
<p>Beck&#8217;s Depression Inventory was administered to assess the symptoms of depression. It is a self-report 4-point Likert-type scale, tested and validated among students in Pakistan (<xref ref-type="bibr" rid="B6">Aqeel et al., 2020</xref>).</p>
</sec>
<sec>
<title>4.2.4 Social Connectedness</title>
<p>The updated Social Connectedness Scale (<xref ref-type="bibr" rid="B51">Lee et al., 2001</xref>) was administered. The instrument consists of 20 items on a 6-point Likert-type scale ranging from 1 to 6. The instrument was found to be a reliable measure for the Pakistani population (<xref ref-type="bibr" rid="B27">Fatima et al., 2017</xref>).</p>
</sec>
<sec>
<title>4.2.5. Religious Orientation</title>
<p>The updated version of the extrinsic and intrinsic Religious Orientation Scale (<xref ref-type="bibr" rid="B3">Allport &amp; Ross, 1967</xref>; <xref ref-type="bibr" rid="B33">Gorsuch &amp; McPherson, 1989</xref>) was administered. The scale consists of 14 items, with 8 items for IRO and 6 items for ERO. The scale has been validated and tested among Muslim students (<xref ref-type="bibr" rid="B73">Rahman et al., 2021</xref>).</p>
</sec>
</sec>
<sec>
<title><italic>4.3 Data Analysis</italic></title>
<p>Statistical Package for the Social Sciences software (version 23) and Hayes&#8217; PROCESS macro (version 3.5.2) were used for data analysis. Pearson&#8217;s Product-Moment Correlation was conducted for bivariate analysis. The statistical significance level was set at p &lt;.05. For moderation analysis, model 1 was used while model 58 was used for moderated mediation, with a bootstrap method with 5000 replications (<xref ref-type="bibr" rid="B37">Hayes, 2017</xref>).</p>
</sec>
</sec>
<sec>
<title>5. Results</title>
<p>Initially, the data were collected from 400 university students. The final sample, after excluding outliers and those meeting inclusion criteria, comprised 372 participants. The respondents ranged in age from 18 to 30 years (M<sub>age</sub> = 22.25, SD = 2.40), and 77.7% of the participants were female. The demographic profile of the participants is mentioned in <xref ref-type="table" rid="T1">Table 1</xref>. Further details regarding the sample are mentioned in the primary study (<xref ref-type="bibr" rid="B62">Muneeb &amp; Hassan, 2023a</xref>).</p>
<table-wrap id="T1">
<label>Table 1</label>
<caption>
<p>Background characteristics of the participants based on their age, gender and level of education.</p>
</caption>
<table>
<tbody>
<tr>
<td align="left" valign="top"><bold>Variable</bold></td>
<td align="left" valign="top"><bold><italic>f</italic></bold></td>
<td align="left" valign="top"><bold>%</bold></td>
</tr>
<tr>
<td align="left" valign="top"><bold>Gender</bold></td>
<td align="left" valign="top"></td>
<td align="left" valign="top"></td>
</tr>
<tr>
<td align="left" valign="top">Male</td>
<td align="left" valign="top">83</td>
<td align="left" valign="top">22.3</td>
</tr>
<tr>
<td align="left" valign="top">Female</td>
<td align="left" valign="top">289</td>
<td align="left" valign="top">77.7</td>
</tr>
<tr>
<td align="left" valign="top"><bold>Age (years)</bold></td>
<td align="left" valign="top"></td>
<td align="left" valign="top"></td>
</tr>
<tr>
<td align="left" valign="top">18&#8211;22</td>
<td align="left" valign="top">159</td>
<td align="left" valign="top">42.7</td>
</tr>
<tr>
<td align="left" valign="top">23&#8211;26</td>
<td align="left" valign="top">110</td>
<td align="left" valign="top">29.6</td>
</tr>
<tr>
<td align="left" valign="top">27&#8211;30</td>
<td align="left" valign="top">103</td>
<td align="left" valign="top">27.7</td>
</tr>
<tr>
<td align="left" valign="top"><bold>Education</bold></td>
<td align="left" valign="top"></td>
<td align="left" valign="top"></td>
</tr>
<tr>
<td align="left" valign="top">Bachelor&#8217;s</td>
<td align="left" valign="top">263</td>
<td align="left" valign="top">70.7</td>
</tr>
<tr>
<td align="left" valign="top">Master&#8217;s</td>
<td align="left" valign="top">104</td>
<td align="left" valign="top">28</td>
</tr>
<tr>
<td align="left" valign="top">PhD</td>
<td align="left" valign="top">5</td>
<td align="left" valign="top">1.3</td>
</tr>
<tr>
<td align="left" valign="top"><bold>Family income</bold></td>
<td align="left" valign="top"></td>
<td align="left" valign="top"></td>
</tr>
<tr>
<td align="left" valign="top">Average</td>
<td align="left" valign="top">103</td>
<td align="left" valign="top">27.7</td>
</tr>
<tr>
<td align="left" valign="top">Above average</td>
<td align="left" valign="top">259</td>
<td align="left" valign="top">72.3</td>
</tr>
</tbody>
</table>
</table-wrap>
<sec>
<title><italic>5.1 Descriptive Statistics and Bivariate Correlations</italic></title>
<p>Pearson product-moment correlation, means, standard deviations, and internal reliability for the scale scores were computed. PS (r = .57, p &lt; .01) and depression (r = .58, p &lt; .01) are significantly and positively related to SI, whereas social connectedness (r = &#8211;.25, p &lt; .01) and intrinsic religious orientation (r = &#8211;.25, p &lt; .01) are significantly and negatively related to SI. There is no significant relationship between ERO and SI (r = &#8211;.033, n = 372, p = .52).</p>
</sec>
<sec>
<title><italic>5.2 Moderating Role of SC in the Association between PS and SI</italic></title>
<p>As shown in <xref ref-type="table" rid="T2">Table 2</xref>, the interaction between PS and SC was negative and statistically significant (&#946; = &#8211;.002, p &lt; 0.05). This identified SC as a moderator in the association between PS and SI, though the interaction value is small (See <xref ref-type="fig" rid="F2">Figure 2</xref>). The conditional direct effect showed corresponding results, being positively and significantly different from zero. The subsequent slope analysis is shown in <xref ref-type="fig" rid="F3">Figure 3</xref>.</p>
<table-wrap id="T2">
<label>Table 2</label>
<caption>
<p>The Mediator Variable Model and Dependent Variable Model.</p>
</caption>
<table>
<tbody>
<tr>
<td align="left" valign="top"></td>
<td align="left" valign="top"><bold>B</bold></td>
<td align="left" valign="top"><bold>SE</bold></td>
<td align="left" valign="top"><bold><italic>p</italic></bold></td>
<td align="left" valign="top"><bold>LLCI</bold></td>
<td align="left" valign="top"><bold>ULCI</bold></td>
</tr>
<tr>
<td align="left" colspan="6" valign="top"><bold>Mediator variable model (Depression)</bold></td>
</tr>
<tr>
<td align="left" valign="top">Constant</td>
<td align="left" valign="top">&#8211;8.50</td>
<td align="left" valign="top">3.05</td>
<td align="left" valign="top">.005</td>
<td align="left" valign="top">&#8211;14.50</td>
<td align="left" valign="top">&#8211;2.49</td>
</tr>
<tr>
<td align="left" valign="top">Age</td>
<td align="left" valign="top">&#8211;.07</td>
<td align="left" valign="top">.36</td>
<td align="left" valign="top">.05</td>
<td align="left" valign="top">&#8211;1.40</td>
<td align="left" valign="top">.017</td>
</tr>
<tr>
<td align="left" valign="top">Gender</td>
<td align="left" valign="top">.06</td>
<td align="left" valign="top">.75</td>
<td align="left" valign="top">.12</td>
<td align="left" valign="top">&#8211;.32</td>
<td align="left" valign="top">2.64</td>
</tr>
<tr>
<td align="left" valign="top">Average family income</td>
<td align="left" valign="top">.11**</td>
<td align="left" valign="top">.67</td>
<td align="left" valign="top">.006</td>
<td align="left" valign="top">.51</td>
<td align="left" valign="top">3.17</td>
</tr>
<tr>
<td align="left" valign="top">Psychological Strain</td>
<td align="left" valign="top">.27***</td>
<td align="left" valign="top">.04</td>
<td align="left" valign="top">.000</td>
<td align="left" valign="top">.19</td>
<td align="left" valign="top">.36</td>
</tr>
<tr>
<td align="left" valign="top">Social Connectedness</td>
<td align="left" valign="top">.07</td>
<td align="left" valign="top">.06</td>
<td align="left" valign="top">.20</td>
<td align="left" valign="top">&#8211;.04</td>
<td align="left" valign="top">.20</td>
</tr>
<tr>
<td align="left" valign="top">PS X SC</td>
<td align="left" valign="top">&#8211;.002**</td>
<td align="left" valign="top">.0006</td>
<td align="left" valign="top">.000</td>
<td align="left" valign="top">&#8211;.0031</td>
<td align="left" valign="top">&#8211;.0009</td>
</tr>
<tr>
<td align="left" colspan="6" valign="top">R<sup>2</sup> = .49***, F = 121.37, &#916;R<sup>2</sup> (After adding interaction 1) = 0.016***</td>
</tr>
<tr>
<td align="left" colspan="6" valign="top"><bold>Dependent Variable Model (Suicidal Ideation)</bold></td>
</tr>
<tr>
<td align="left" valign="top">Constant</td>
<td align="left" valign="top">5.37</td>
<td align="left" valign="top">3.57</td>
<td align="left" valign="top">.13</td>
<td align="left" valign="top">&#8211;1.65</td>
<td align="left" valign="top">12.39</td>
</tr>
<tr>
<td align="left" valign="top">Age</td>
<td align="left" valign="top">.005</td>
<td align="left" valign="top">.42</td>
<td align="left" valign="top">.88</td>
<td align="left" valign="top">&#8211;.76</td>
<td align="left" valign="top">.88</td>
</tr>
<tr>
<td align="left" valign="top">Gender</td>
<td align="left" valign="top">&#8211;.009</td>
<td align="left" valign="top">.87</td>
<td align="left" valign="top">.82</td>
<td align="left" valign="top">&#8211;1.91</td>
<td align="left" valign="top">1.52</td>
</tr>
<tr>
<td align="left" valign="top">Average family income</td>
<td align="left" valign="top">&#8211;.019</td>
<td align="left" valign="top">.79</td>
<td align="left" valign="top">.64</td>
<td align="left" valign="top">&#8211;1.91</td>
<td align="left" valign="top">1.19</td>
</tr>
<tr>
<td align="left" valign="top">Psychological Strain</td>
<td align="left" valign="top">.10***</td>
<td align="left" valign="top">.01</td>
<td align="left" valign="top">.000</td>
<td align="left" valign="top">.07</td>
<td align="left" valign="top">.13</td>
</tr>
<tr>
<td align="left" valign="top">Depression</td>
<td align="left" valign="top">.81***</td>
<td align="left" valign="top">.18</td>
<td align="left" valign="top">.000</td>
<td align="left" valign="top">.44</td>
<td align="left" valign="top">1.18</td>
</tr>
<tr>
<td align="left" valign="top">Social Connectedness</td>
<td align="left" valign="top">.10***</td>
<td align="left" valign="top">.03</td>
<td align="left" valign="top">.004</td>
<td align="left" valign="top">.03</td>
<td align="left" valign="top">.17</td>
</tr>
<tr>
<td align="left" valign="top">PS X SC (Interaction 1)</td>
<td align="left" valign="top">&#8211;.002**</td>
<td align="left" valign="top">.0006</td>
<td align="left" valign="top">.000</td>
<td align="left" valign="top">&#8211;.0031</td>
<td align="left" valign="top">&#8211;.0009</td>
</tr>
<tr>
<td align="left" valign="top">Depression X SC (Interaction 2)</td>
<td align="left" valign="top">&#8211;.0053*</td>
<td align="left" valign="top">.002</td>
<td align="left" valign="top">.04</td>
<td align="left" valign="top">&#8211;.01</td>
<td align="left" valign="top">&#8211;.0001</td>
</tr>
<tr>
<td align="left" colspan="6" valign="top">R<sup>2</sup> = .42***, F = 66.97, &#916;R<sup>2</sup> (After adding interaction 2) = .006**</td>
</tr>
</tbody>
</table>
<table-wrap-foot>
<fn><p>Note: *p &lt; .05, **p &lt; .01, ***p &lt; .001.</p></fn>
<fn><p>PS: Psychological strain, SC: Social connectedness.</p></fn>
</table-wrap-foot>
</table-wrap>
<fig id="F2">
<label>Figure 2</label>
<caption>
<p>Illustration of the Statistical Model of the Study.</p>
</caption>
<graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="jmmh-5390_hassan-g2.png"/>
</fig>
<fig id="F3">
<label>Figure 3</label>
<caption>
<p>Social connectedness as a moderator in the relationship between PS and SI, indicating that at higher level of connectedness, less PS and less ideation is experienced.</p>
</caption>
<graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="jmmh-5390_hassan-g3.png"/>
</fig>
</sec>
<sec>
<title><italic>5.3 Moderation of SC in the Association between PS and SI via Depression</italic></title>
<p>As shown in <xref ref-type="table" rid="T2">Table 2</xref>, after controlling for covariates, PS positively predicted depression (&#946; = .27, p &lt; 0.001). In addition, PS (&#946; = 0.10, p &lt; 0.001) and depression (&#946; = 0.81, p &lt; 0.001) positively predicted SI. The paths between PS and depression (&#946; = &#8211;.002, p &lt; 0.001) and between depression and SI (&#946; = &#8211;.0053, p &lt; 0.05) were significantly moderated by SC. All three conditional direct effects were positively and significantly different from zero, indicating significant moderation of SC on SI. Subsequent simple slope analyses are shown (see <xref ref-type="fig" rid="F4">Figure 4</xref>). No index of moderated mediation is produced in Model 58, but the pairwise contrasts of indirect effect were all significant, indicating that the indirect effects were conditional on the level of the moderator.</p>
<fig id="F4">
<label>Figure 4</label>
<caption>
<p>Social connectedness as a moderator in the relationship between depression and suicidal ideation, showing reduced suicidal ideation at higher levels of connectedness.</p>
</caption>
<graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="jmmh-5390_hassan-g4.png"/>
</fig>
</sec>
<sec>
<title><italic>5.4 Moderating Role of IRO in the Association between PS and SI</italic></title>
<p>As shown in <xref ref-type="table" rid="T3a">Table 3a</xref>, the interaction between PS and IRO was negative and statistically significant (&#946; = &#8211;.002, p &lt; 0.05). This identified IRO as a moderator in the association between PS and SI, though the interaction value is small (See <xref ref-type="fig" rid="F5a">Figure 5a</xref>). The conditional direct effect showed corresponding results (See <xref ref-type="table" rid="T3b">Table 3b</xref>), positively and significantly different from zero. The subsequent slope analysis is shown in <xref ref-type="fig" rid="F5b">Figure 5b</xref>.</p>
<table-wrap id="T3a">
<label>Table 3a</label>
<caption>
<p>Intrinsic Religiosity as a Moderator in the Relationship between Psychological Strain and Suicidal Ideation.</p>
</caption>
<table>
<tbody>
<tr>
<td align="left" valign="top"></td>
<td align="left" valign="top"><bold>B</bold></td>
<td align="left" valign="top"><bold>SE</bold></td>
<td align="left" valign="top"><bold><italic>p</italic></bold></td>
<td align="left" valign="top"><bold>LLCI</bold></td>
<td align="left" valign="top"><bold>ULCI</bold></td>
</tr>
<tr>
<td align="left" colspan="6" valign="top"><bold>Dependent Variable Model (Suicidal Ideation)</bold></td>
</tr>
<tr>
<td align="left" valign="top">Constant</td>
<td align="left" valign="top">&#8211;11.73</td>
<td align="left" valign="top">9.12</td>
<td align="left" valign="top">.19</td>
<td align="left" valign="top">&#8211;29.68</td>
<td align="left" valign="top">6.22</td>
</tr>
<tr>
<td align="left" valign="top">Age</td>
<td align="left" valign="top">&#8211;.26</td>
<td align="left" valign="top">.60</td>
<td align="left" valign="top">.66</td>
<td align="left" valign="top">&#8211;1.45</td>
<td align="left" valign="top">.92</td>
</tr>
<tr>
<td align="left" valign="top">Gender</td>
<td align="left" valign="top">.73</td>
<td align="left" valign="top">.92</td>
<td align="left" valign="top">.42</td>
<td align="left" valign="top">&#8211;1.08</td>
<td align="left" valign="top">2.55</td>
</tr>
<tr>
<td align="left" valign="top">Average family income</td>
<td align="left" valign="top">.40</td>
<td align="left" valign="top">.82</td>
<td align="left" valign="top">.62</td>
<td align="left" valign="top">&#8211;1.22</td>
<td align="left" valign="top">2.02</td>
</tr>
<tr>
<td align="left" valign="top">Psychological Strain</td>
<td align="left" valign="top">.35**</td>
<td align="left" valign="top">.07</td>
<td align="left" valign="top">.000</td>
<td align="left" valign="top">.19</td>
<td align="left" valign="top">.50</td>
</tr>
<tr>
<td align="left" valign="top">Intrinsic religiosity</td>
<td align="left" valign="top">.44</td>
<td align="left" valign="top">.27</td>
<td align="left" valign="top">.10</td>
<td align="left" valign="top">&#8211;.09</td>
<td align="left" valign="top">.98</td>
</tr>
<tr>
<td align="left" valign="top">PS X IR</td>
<td align="left" valign="top">&#8211;.006*</td>
<td align="left" valign="top">.002</td>
<td align="left" valign="top">.01</td>
<td align="left" valign="top">&#8211;.011</td>
<td align="left" valign="top">&#8211;.001</td>
</tr>
<tr>
<td align="left" colspan="6" valign="top">R<sup>2</sup> = .37**, F = 19.26, &#916; R<sup>2</sup> after adding interaction 1 = 0.01*</td>
</tr>
</tbody>
</table>
</table-wrap>
<fig id="F5a">
<label>Figure 5a</label>
<caption>
<p>Statistical Model of Intrinsic Religiosity as a Moderator between Psychological Strain and Suicidal Ideation.</p>
</caption>
<graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="jmmh-5390_hassan-g5.png"/>
</fig>
<table-wrap id="T3b">
<label>Table 3b</label>
<caption>
<p>Conditional direct effect analysis indicating significant moderation of IR with SI.</p>
</caption>
<table>
<tbody>
<tr>
<td align="left" valign="top"><bold>Conditional direct effect analysis at IR = M&#177; SD</bold></td>
<td align="left" valign="top"><bold>B</bold></td>
<td align="left" valign="top"><bold>SE</bold></td>
<td align="left" valign="top"><bold>LLCI</bold></td>
<td align="left" valign="top"><bold>ULCI</bold></td>
</tr>
<tr>
<td align="left" valign="top">M- 1SD (24.89)</td>
<td align="left" valign="top">.18**</td>
<td align="left" valign="top">.01</td>
<td align="left" valign="top">.15</td>
<td align="left" valign="top">.22</td>
</tr>
<tr>
<td align="left" valign="top">M (29.87)</td>
<td align="left" valign="top">.15**</td>
<td align="left" valign="top">.01</td>
<td align="left" valign="top">.13</td>
<td align="left" valign="top">.18</td>
</tr>
<tr>
<td align="left" valign="top">M+ 1SD (34.85)</td>
<td align="left" valign="top">.12**</td>
<td align="left" valign="top">.01</td>
<td align="left" valign="top">.08</td>
<td align="left" valign="top">.15</td>
</tr>
</tbody>
</table>
<table-wrap-foot>
<fn><p>Confidence Interval 95% was adopted. IR = Intrinsic Religiosity.</p></fn>
<fn><p>CI = Confidence Interval, LL = Lower Limit, UL = Upper limit, **p &lt; .01.</p></fn>
</table-wrap-foot>
</table-wrap>
<fig id="F5b">
<label>Figure 5b</label>
<caption>
<p>Intrinsic Religious Orientation as a Moderator between Psychological Strain and Suicidal Ideation indicating RO mitigating the impact of PS on SI.</p>
</caption>
<graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="jmmh-5390_hassan-g6.png"/>
</fig>
</sec>
</sec>
<sec>
<title>6. Discussion</title>
<p>Pakistan ranks as the fifth most populous country in the world with a population of more than 241 million, with the largest number of people (64%) under 30 (<xref ref-type="bibr" rid="B68">Pakistan Bureau of Statistics, 2023</xref>). Unfortunately, most of the suicides in Pakistan occur under the age of 30. The suicide mortality rate of Pakistan is 9.77 per 100,000 population (<xref ref-type="bibr" rid="B94">WHO, 2020</xref>), yet the figure is largely underestimated due to underreporting tied to the pervasive societal stigma against suicide. There is a paucity of literature dedicated to suicide in Pakistan, and even less on prevention and protective factors. Our study aims to bridge the knowledge gaps and explore the underlying mechanisms behind SI to make a case for early intervention before its progression to suicide.</p>
<sec>
<title><italic>6.1 Bivariate analysis</italic></title>
<p>Social determinants, like SC, play a significant role in preventing suicidal thoughts and behavior. Our findings reveal that SC was negatively and significantly related to SI, indicating that an increase in connectedness is associated with a decrease in suicidal thoughts. As the perception of connectedness increases in a young individual, the chance of thinking about ending one&#8217;s life decreases. Hence, the hypothesis is supported. Loss of sense of connectedness and chronic isolation can be traumatic (<xref ref-type="bibr" rid="B52">Lee &amp; Robbins, 1995</xref>, <xref ref-type="bibr" rid="B53">1998</xref>; <xref ref-type="bibr" rid="B91">Wickramaratne et al., 2022</xref>), facilitating an individual toward suicidal thoughts (<xref ref-type="bibr" rid="B101">Zhang, 2019</xref>). The findings are empirically supported by related studies conducted in Pakistan, as disrupted social networks (<xref ref-type="bibr" rid="B78">Shekhani et al., 2018</xref>) and poor interaction with family (<xref ref-type="bibr" rid="B32">Ghazanfar et al., 2015</xref>) played a critical role in predicting SI. Similarly, social isolation, exposure to family violence, and loss or separation of parents were found as significant risk factors for suicide (<xref ref-type="bibr" rid="B85">Tharwani et al., 2023</xref>). Hence, SC significantly influences an individual&#8217;s intent to live, be it with peers, parents, or school.</p>
<p>Another noteworthy social determinant of SI, in the context of Pakistan being a Muslim-majority country, is IRO. Findings reveal that IRO has a significant negative but small association with SI, supporting our hypothesis that an increase in IRO is related to a decrease in SI. Young adults who find meaning in religion and follow it as an ultimate end are less likely to think about ending their lives. The findings of the study are in line with the literature and theory that people who are religiously involved are more likely to be protected from suicide (<xref ref-type="bibr" rid="B24">De Berardis et al., 2020</xref>; <xref ref-type="bibr" rid="B50">Lawrence et al., 2016</xref>).</p>
<p>Contrarily, there is no significant relationship between ERO and SI, and the hypothesis was not supported. Findings suggest that changes in the level of ERO will not be related to SI. The nature of RO might be the reason behind the relationship. When RO is intended to serve as an instrument for social recognition or self-esteem, it might not be related to a decrease in SI. In literature, ERO is seen as less indicative of mental health as compared to the IRO due to their nature and intention (<xref ref-type="bibr" rid="B3">Allport &amp; Ross, 1967</xref>; <xref ref-type="bibr" rid="B29">Garc&#237;a-Alandete &amp; Bernab&#233;-Valero, 2013</xref>). Even in China, university students with high IRO and low personality-oriented ERO intend to have lower suicidality (<xref ref-type="bibr" rid="B55">Lew et al., 2018</xref>). IRO embodied positive outcomes, whereas ERO embodied negative outcomes. Findings are supported by similar conclusions, where religious attendance only mitigated distress when experiencing high spirituality (<xref ref-type="bibr" rid="B45">Kidwai et al., 2014</xref>). Empirical and theoretical evidence reinforces the above-stated results that intrinsically oriented religious people have better mental health as compared to extrinsically oriented religious, and are less likely to suffer from suicidal thoughts (<xref ref-type="bibr" rid="B3">Allport &amp; Ross, 1967</xref>; <xref ref-type="bibr" rid="B29">Garc&#237;a-Alandete &amp; Bernab&#233;-Valero, 2013</xref>).</p>
</sec>
<sec>
<title><italic>6.2 Moderation analysis</italic></title>
<p>A moderation analysis was carried out to study the role of SC in the association between PS and SI. A moderated mediation model was tested to explore the role of SC as a moderator in the mediation of depression between PS and SI. Also, a moderation analysis was carried out to study the role of IRO in the association between PS and SI. The findings revealed that SC and IRO buffer the effect of PS on SI. Also, depression may not mediate between PS and SI when a young person has a high sense of connectedness.</p>
<sec>
<title>6.2.1 Moderating Role of SC in the Association between PS and SI</title>
<p>A young Muslim student experiencing PS is less likely to have suicidal thoughts when socially connected. A lack of SC will not cause the person to think about suicide, but can facilitate SI in the presence of other strains (<xref ref-type="bibr" rid="B101">Zhang, 2019</xref>). Low-connected individuals perceive their environment as cold and negative, eventually leading to isolation and frustration (<xref ref-type="bibr" rid="B51">Lee et al., 2001</xref>; <xref ref-type="bibr" rid="B53">Lee &amp; Robbins, 1998</xref>). This isolation and feelings of loneliness predict SI (<xref ref-type="bibr" rid="B60">McClelland et al., 2020</xref>; <xref ref-type="bibr" rid="B81">Stravynski &amp; Boyer, 2001</xref>). The impact of PS on SI was greater among low-connected young adults than those with a high level of SC. Young adults who perceive themselves as more socially connected are less likely to contemplate ending their lives when suffering from strain as compared to those who perceive themselves as less connected. Also, for highly connected individuals, SC will reverse the effect of strains and eventually prevent SI. Hence, the hypothesis is supported. Protective elements can avert the impact of risk factors against SI, whereas loneliness strongly predicts SI (<xref ref-type="bibr" rid="B77">S&#225;nchez-Teruel &amp; Robles-Bello, 2014</xref>; <xref ref-type="bibr" rid="B89">Wang et al., 2025</xref>). Family togetherness and peer support are found as buffering agents against SI even among bullying victims (<xref ref-type="bibr" rid="B10">Arango et al., 2019</xref>). Promoting connectedness can be a prospective target of interventions against high-risk youth, as it can act as a protective factor (<xref ref-type="bibr" rid="B89">Wang et al., 2025</xref>). The current findings are in line with the literature, as for an individual who has suicide in mind, SC can reduce the level of SI by acting as a buffering agent, even when PS is present (<xref ref-type="bibr" rid="B101">Zhang, 2019</xref>).</p>
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<title>6.2.3 Moderation of SC in the Association between PS and SI via Depression</title>
<p>As the level of PS increases in young students, they are more likely to look for an escape and contemplate ending their lives. The discrepancies in real and ideal life, aspiration and reality, relative deprivation, and the lack of coping abilities frustrate youth, driving them to get rid of the mental torment by exploring the option of ending their lives (<xref ref-type="bibr" rid="B101">Zhang, 2019</xref>). Similarly, an increase in depressive symptoms is related to an escalation in suicidal thoughts among university students. Depression is the strongest predictor of SI (<xref ref-type="bibr" rid="B64">Mustaffa et al., 2014</xref>; <xref ref-type="bibr" rid="B74">Ran et al., 2015</xref>), making youth suffering from depression vulnerable to SI. Similarly, depression was found to be a mediator between coping strain and SI (<xref ref-type="bibr" rid="B84">Tauqeer et al., 2024</xref>).</p>
<p>Depression is the most debilitating mental disorder, with global prevalence rates of depression as 4.4% (<xref ref-type="bibr" rid="B93">WHO, 2017</xref>). In Pakistan, the prevalence of depression is estimated to range from 22% to 67% (<xref ref-type="bibr" rid="B4">Altaf, 2015</xref>). Preventive strategies must be employed, as the country has one of the lowest psychiatrist-to-population ratios worldwide (<xref ref-type="bibr" rid="B94">WHO, 2020</xref>). More than 90% of individuals who die by suicide suffer from psychiatric illness, so recognizing SI in patients presents a crucial opportunity to evaluate and intervene (<xref ref-type="bibr" rid="B58">Mann et al., 2021</xref>). Talking to someone trustworthy (59.5%) and praying to God (56.5%) were regarded as the best treatments for depression by patients (<xref ref-type="bibr" rid="B67">Nisar et al., 2019</xref>), hence reinforcing our findings, which suggest intervention against SI and depression with protective factors such as SC and RO. Young Pakistani students might find themselves stuck between the values of two generations (value strain); they may feel they are not rewarded the way they deserve (aspiration strain); or they may feel that others are rewarded more with the same effort (deprivation strain); or they may feel that their situation is way beyond their abilities to cope (coping strain). The inherent sense of belongingness with parents, peers, and the social world can prevent them from thinking of death as an ultimate solution to their problems. Their overall high sense of attachment to the community would buffer the impact of strains faced in life (<xref ref-type="bibr" rid="B101">Zhang, 2019</xref>).</p>
<p>Our study indicated that both direct and indirect effects of PS on SI are moderated by SC. Social connectedness will buffer the impact of PS on depression and the impact of depression on SI. In other words, the mediation of depression in the association between PS and SI is conditional upon the individual&#8217;s levels of connectedness. This indicates that even in the presence of PS, a connection with a social world can help to avoid symptoms of depression, and thoughts of suicide can be prevented. Highly connected people may attempt to escape the vicious cycle of strains, which lead to depressive symptoms and eventually to suicidal thoughts via their inherent pervasive sense of intimacy with their social relationships. Contrarily, with a low sense of connectedness, symptoms of depression may be exacerbated due to strains in life, and may lead one to contemplate suicide. The findings of this study are empirically supported as low-connected individuals tend to perceive their environment as cold and negative, eventually leading to isolation and frustration (<xref ref-type="bibr" rid="B51">Lee et al., 2001</xref>; <xref ref-type="bibr" rid="B53">Lee &amp; Robbins, 1998</xref>), which predict SI (<xref ref-type="bibr" rid="B81">Stravynski &amp; Boyer, 2001</xref>; <xref ref-type="bibr" rid="B101">Zhang, 2019</xref>). Empirically, SC protects from depressive symptoms and disorders across diverse settings and populations (<xref ref-type="bibr" rid="B91">Wickramaratne et al., 2022</xref>). It also predicts social well-being and high achievement among university students (<xref ref-type="bibr" rid="B39">HM, 2021</xref>).</p>
<p>As the COVID-19 pandemic had a colossal impact on the social and psychological health of Pakistani students, it was found that concerns regarding performance, semester completion, and online teaching were further damaging the mental health of students (<xref ref-type="bibr" rid="B12">Baloch et al., 2021</xref>). Another study found that SC obtained through online sources can help students develop more social skills and feel increased levels of connectedness and contentment (<xref ref-type="bibr" rid="B82">Sultan et al., 2020</xref>).</p>
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<sec>
<title>6.2.4 Moderation of IRO in the Association between PS and SI</title>
<p>An intrinsically oriented religious person is less likely to think about suicide when faced with PS. When religion serves as a foundation of choices and meaning in life for an individual, it acts as a buffering agent against strains. For an IRO, religion is an ultimate end in itself, acting as a protective agent against psychological strains and suicidal thoughts. A person who is suffering from relative deprivation, value strain, aspiration, or coping strain may find hope in religion. For IRO, values and lives are established by and for religion, and hence their aspirations and deprivations may be defined by religion. Intrinsically oriented people benefit more from a religious identity because religion can give them purpose and can frame their experiences (<xref ref-type="bibr" rid="B5">Andrus, 2022</xref>). They are exhilarated by the promise of spiritual development and a deeper relationship with God, which may help them cope better with situations (Hills et al., 2004; <xref ref-type="bibr" rid="B40">Hunter &amp; Merrill, 2013</xref>). People who are religiously involved are more likely to be protected from suicide (Durkheim, 1897; <xref ref-type="bibr" rid="B2">Allport, 1963</xref>). This is in line with literature, as RO buffers against psychological distress (<xref ref-type="bibr" rid="B17">Butt, 2014</xref>; Laher, 2007).</p>
<p>The conditional direct effect of PS on SI showed that there will be less impact of PS on SI for a young adult who is more intrinsically religious as compared to one who is less. When religion is viewed as an ultimate end, it is less likely that the person thinks about ending their life in the presence of PS. Lack of RO can act as a risk factor for SI in the presence of PS (Durkheim, 1897). Similar findings were reported in other studies in which RO was negatively related to stress (<xref ref-type="bibr" rid="B17">Butt, 2014</xref>; Laher, 2007). As with PS, religion was found as a risk element among the Chinese sample (<xref ref-type="bibr" rid="B106">Zhang et al., 2011</xref>; <xref ref-type="bibr" rid="B103">Zhang, et al., 2016</xref>), which might be attributed to the Chinese culture being officially an atheist country and where religious practices are considered deviant behavior (Zhang, 2010; Zhang &amp; Xu, 2007). By contrast, the protective role of religion and spirituality has been indicated in systemic reviews and other studies of many religions, such as Judaism, Christianity, Hinduism, and Islam (<xref ref-type="bibr" rid="B1">Abdollahi et al., 2015</xref>; <xref ref-type="bibr" rid="B30">Gearing &amp; Alonzo, 2009</xref>; <xref ref-type="bibr" rid="B49">Koenig et al., 2005</xref>).</p>
<p>Another interesting insight was provided by a prospective nationwide survey, which highlighted that participation in religious activities and not mere religious affiliation has a protective role against suicidal death (<xref ref-type="bibr" rid="B47">Kleiman &amp; Liu, 2018</xref>). Active involvement in religious activities and seeking spiritual benefits has a protective role. Buzdar et al. (<xref ref-type="bibr" rid="B18">2020</xref>) reported that IRO and not ERO is protective against disordered social media use among young Muslim students. Rather, the higher ERO is related to an increase in disordered social media usage. One of the reasons for this might be that, among the educated Muslim sample, religion is adopted in its conventional way, with no room for skepticism or questioning. People in Pakistan are a Muslim majority, and they support the transmission of intrinsic religion rather than inquisitive teaching and learning of religion (<xref ref-type="bibr" rid="B19">Buzdar et al., 2019</xref>, <xref ref-type="bibr" rid="B65">Nadeem et al., 2019</xref>).</p>
</sec>
</sec>
<sec>
<title><italic>6.3 Implications</italic></title>
<p>With more than 64% of the population of Pakistan highly vulnerable to suicide, a poor mental healthcare system, and the impacts of the COVID-19 outbreak, interventions against SI are crucial to prevent ideation. Without timely intervention, our young students might succumb to SI.</p>
<p>Unfortunately, the country does not have an integrated strategic policy framework for suicide prevention at the national, provincial, or local levels. Mental health action plans are available, but implementation is lacking at both the national and provincial levels, with mere replication of mental health acts. This study underscores the importance of preventive strategies at the national level, with radical steps for policy change and implementation.</p>
<p>Mental health awareness campaigns must be introduced to educate youth, encourage help-seeking behavior, and mitigate the societal stigma and discrimination against mental disorders and suicidality. Public health initiatives can prevent SI by implementing multifaceted interventions. State and humanitarian agencies must facilitate digital services after COVID-19 to ensure scalable and accessible mental health care. Institutions must establish online platforms to provide counseling and SS for students&#8217; mental and social well-being. Services like internet-based cognitive behavioral therapy might be introduced with data protection protocols to ensure help-seeking against depression and suicide without worrying about the associated stigma.</p>
<p>The present study has clinical implications for suicide prevention among young Muslim students. Historically, religion and psychotherapy were segregated, and psychotherapists were not considered prepared to address spiritual issues in psychotherapy (<xref ref-type="bibr" rid="B69">Pargament &amp; Saunders, 2007</xref>). In the Islamic Republic of Pakistan, religion guides the way of life and IRO has a protective role against SI among university students. The Royal College of Psychiatrists (<xref ref-type="bibr" rid="B21">Cook, 2013</xref>) upholds the significance of addressing religion in clinical practice. A psychologist cannot inculcate religion, but for someone whose lifestyle is guided by religion, their religious conflicts and strains need to be addressed. If patients report being religious during history-taking and are comfortable in discussing their religious concerns, mental health practitioners must be open to addressing such issues or refer the patient to another practitioner who is equipped to meet their needs (<xref ref-type="bibr" rid="B88">VanderWeele et al., 2017</xref>). In the last two decades, there has been a shift in the realm of psychotherapy, where psychotherapists are prepared to address religious concerns in treatment (<xref ref-type="bibr" rid="B70">Post &amp; Wade, 2009</xref>). Hence, therapy must be tailored to fit the client&#8217;s spiritual and social needs without imposing any practice (<xref ref-type="bibr" rid="B96">Worthington &amp; Aten, 2009</xref>), to facilitate well-being by using these resources in their favor (<xref ref-type="bibr" rid="B31">Ghafoor et al., 2022</xref>) with the help of professionals.</p>
</sec>
<sec>
<title><italic>6.4 Limitations and Recommendations</italic></title>
<p>This study aimed to address SI while suicide attempts and suicidal behavior remained unaddressed. Future studies can aim to study the mechanisms that lead to suicide ideation, attempt, and behavior. Since self-report measures were administered, social desirability and biases in reporting could be observed. Future studies can employ other methods for data collection, such as interviews, focus group discussions, etc. The correlational design of the study prevents causal inferences; hence, definitive conclusions must therefore be avoided. This study only offers one exploration of the pathway to SI, presenting the plausible association between variables. In the future, prospective studies may help to determine causal inferences and suggest comprehensive insight into other pathways. As the study employed a convenience sampling technique, it mandates a cautious interpretation of the findings. Though the study addressed certain psychosocial factors regarding SI, other pathways are yet to be explored. Lastly, as this study was carried out during the COVID-19 outbreak among Muslim students, and the findings must be assessed against other samples without the impact of the pandemic.</p>
</sec>
</sec>
<sec>
<title>7. Conclusion</title>
<p>This study&#8217;s findings underscore the universal importance of protective factors like SC and RO in mitigating suicidal risk. It helps to make a case for policymakers to collaborate and intervene against suicide at the ideation phase and prevent it before its progression to behavior.</p>
</sec>
</body>
<back>
<sec>
<title>Acknowledgment</title>
<p>The authors want to express their gratitude to all the participants for their valuable contributions. Special thanks to the authors for administering their instruments and for supporting the expansion of their work in the Pakistani cultural context.</p>
</sec>
<sec>
<title>Data Availability Statement</title>
<p>Data and materials for the present study have not been made publicly available due to privacy concerns. Data analyzed in the current study are available on request from the corresponding author via email at <ext-link ext-link-type="uri" xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="mailto:dr.sumara@s3h.nust.edu.pk">dr.sumara@s3h.nust.edu.pk</ext-link></p>
</sec>
<sec>
<title>Ethical Approval</title>
<p>This study was conducted in accordance with the ethical guidelines provided by the American Psychological Association and the ethical committee of the National University of Sciences and Technology (Ref: 0801/02/fac-offr/s3h). The anonymity of participants was maintained, and their confidentiality was ensured. Participants had the right to withdraw at any stage of the research process without any consequences.</p>
</sec>
<sec>
<title>Funding</title>
<p>This study was not funded by any organization.</p>
</sec>
<sec>
<title>Informed Consent</title>
<p>Written informed consent was obtained from all individual participants included in the study.</p>
</sec>
<sec>
<title>Consent for Publication</title>
<p>The authors have agreed upon the publication of this manuscript.</p>
</sec>
<sec>
<title>Conflicts of interest</title>
<p>The authors have no conflicts to declare.</p>
</sec>
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