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What are we M-ISSing? Evaluating the Impact of Injuries Not Included in the N/ISS Calculation

Authors: Vibav H Mouli ( University of Michigan Medical School) , John W Scott ( University of Michigan) , Mark Hemmila ( University of Michigan) , Raymond Jean ( University of Michigan) , Bryant W Oliphant ( University of Michigan)

  • What are we M-ISSing? Evaluating the Impact of Injuries Not Included in the N/ISS Calculation

    Abstract Articles

    What are we M-ISSing? Evaluating the Impact of Injuries Not Included in the N/ISS Calculation

    Authors: , , , ,

Keywords: injury severity score , trauma , musculoskeletal , rehabilitation , NISS

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Introduction

The Injury Severity Score (ISS) and New Injury Severity Score (NISS) are known predictors of outcomes such as mortality, ICU admission, and hospital length of stay1-7. However, these calculations only use the three highest Abbreviated Injury Scale (AIS) scores and do not include information about other sustained injuries5,6. It is unclear if incorporating the total count of the patient’s injuries would help in predicting post-discharge utilization. Further, specific body region injury categories (e.g., musculoskeletal) may affect discharge outcomes more than others. In this study, we quantified the number of patient injuries that were not included in the NISS calculation and evaluated whether these “missed” injuries predict discharge destination.

Methods

Data from a statewide trauma quality improvement program from 1/1/2015-12/31/2022 was utilized. Adult patients (≥18yrs) were included, and those that died during admission were excluded. The number of total injuries in each AIS body region subcategory was counted. We assessed the total number of injuries for each patient that was not included in the NISS calculation and an ANOVA to assess missed injuries across NISS categories. A multivariable logistic regression controlling for NISS and other trauma-related covariates was performed to evaluate the likelihood of a patient being discharged to a rehabilitation facility.

Results

There were 211,949 patients that met inclusion criteria with a mean of 1.33±2.5 injuries not included after the NISS was calculated. With increasing NISS categories, there was a significant increase in the mean number of injuries not included (NISS 5-15: 0.62 injuries±1.36; NISS 16-24: 2.57±2.81; NISS 25-35: 4.24±4.31; NISS>35: 6.05±4.73, p<0.001). The number of extremity, abdominal, chest, and head/neck injuries and higher NISS categories were associated with an increased likelihood of being discharged to a rehabilitation facility. (Table)

Tables & Figures

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References

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  2. Shi J, Shen J, Zhu M, Wheeler KK, Lu B, Kenney B, Nuss KE, Xiang H. A new weighted injury severity scoring system: better predictive power for adult trauma mortality. Inj Epidemiol. 2019 Sep 23;6:40. doi: 10.1186/s40621-019-0217-8. PMID: 31559123; PMCID: PMC6755696.

  3. Tohira H, Jacobs I, Mountain D, Gibson N, Yeo A. Systematic review of predictive performance of injury severity scoring tools. Scand J Trauma Resusc Emerg Med. 2012 Sep 10;20:63. doi: 10.1186/1757-7241-20-63. PMID: 22964071; PMCID: PMC3511252.

  4. Meredith JW, Evans G, Kilgo PD, MacKenzie E, Osler T, McGwin G, Cohn S, Esposito T, Gennarelli T, Hawkins M, Lucas C, Mock C, Rotondo M, Rue L. A Comparison of the Abilities of Nine Scoring Algorithms in Predicting Mortality. J Trauma. 2002;53(4):621–8.

  5. Osler T, Baker S, Long W. A Modification of the injury Severity Score that Both Improves Accuracy and Simplifies Scoring. J Trauma. 1997;43(6):922–6.

  6. Stevenson M, Segui-Gomez M, Lescohier I, Di Scala C, McDonald-Smith G. An overview of the injury severity score and the new injury severity score. Inj Prev. 2001 Mar;7(1):10-3. doi: 10.1136/ip.7.1.10. PMID: 11289527; PMCID: PMC1730702.

  7. Balogh ZJ, Varga E, Tomka J, Süveges G, Tóth L, Simonka JA. The new injury severity score is a better predictor of extended hospitalization and intensive care unit admission than the injury severity score in patients with multiple orthopaedic injuries. J Orthop Trauma. 2003 Aug;17(7):508-12. doi: 10.1097/00005131-200308000-00006. PMID: 12902789.

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Published on
13 Dec 2025
Peer Reviewed

Publication details

  • Article Number: 27

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